@article{Dubrovskyi_Dons’koi_2020, title={DYNAMICS OF COVID-19 SPECIFIC G-CLASS IMMUNOGLOBULINS LEVELS IN PATIENTS AFTER THE RECOVERY}, url={https://liksprava.com/index.php/journal/article/view/392}, DOI={10.31640/JVD.3-4.2020(1)}, abstractNote={<p><strong>Introduction. </strong>This article is devoted to determining the level of protective antibodies of the patients at the early and further stages after being suffered from COVID-19.</p> <p><strong>Materials and methods. </strong>On the first stage of the research 66 patients of different age&nbsp; and gender were examined. All patients, with no exception, had positive PCR results on COVID-19. All patients were&nbsp; relatively divided into two age groups: from&nbsp; 18&nbsp; to&nbsp; 39&nbsp;&nbsp; (n = 39) and from 40 to 65 (n = 27). The light form of disease was detected in 40 patients, the moderate form – in 15 and the severe one – in other 3 patients. 8 people&nbsp; were ill without symptoms. There were 11 patients hospitalized at the department of infectious diseases of the hospital. Afterwards the level of the antibodies was controlled&nbsp; on the 60th, 90th and 150th day after the onset. All patients were tested for antibodies to COVID-19 by enzyme-linked immunosorbent assay (ELISA) performed on the equip- ment: enzyme-linked immunosorbent assay Tecan (Austria); PW 40 Microplate Washer (France). ELISA set for serology COVID-19 test system IgG SARS-CoV-2 VitroTest (Ukraine).</p> <p><strong>Results. </strong>Analyzing the data obtained via laboratory research, it can be seen that the immune response to COVID-19 was formed in 82 % of the examined patients.&nbsp;&nbsp; The maximum level of antibodies, which remains as such up to 40th day.</p> <p><strong>Results. </strong>IgG&nbsp; increases from 12 to 40 days and then has not changed significantly for 60; 90 and 150 days. Only 4 patients had a noticeable decrease on day 150 (however, they still had a positive level).</p> <p><strong>Conclusion. </strong>IgG levels in patients with Sars-Cov2 remain high for at&nbsp;&nbsp; least 150 days. The formation of antibodies is not affected by the age difference, neither depends on the severity of the disease.</p&gt;}, number={3-4}, journal={Likars’ka sprava}, author={Dubrovskyi, E. I. and Dons’koi, B. V.}, year={2020}, month={Jun.}, pages={3-8} }