• P. V. Lakatosh Bogomolets National Medical University
  • L. O. Stechenko Bogomolets National Medical University
  • V. P. Lakatosh Bogomolets National Medical University
  • I. V. Poladich Bogomolets National Medical University
  • M. I. Antonyuk Bogomolets National Medical University
  • O. L. Dola Bogomolets National Medical University
Keywords: placenta previa; bleeding; placenta; electron microscopy.


The article presents modern phenomena about electron microscopic features of the studied placentas. Placenta previa is an urgent problem of modern obstetrics, as it is the main cause of obstetric bleeding in the third trimester of pregnancy. The aim of the study was to study the electron microscopic features of the myometrium of the lower uterine segment in women with placenta previa. Materials and methods. In accordance with the aim of the research, 122 pregnant women with atypical location of the placenta were examined, who were hospitalized and delivered in the Perinatal Center of Kyiv during 20140–2020 at 36 + 6 days and 38–39 weeks of gestation. In 10 pregnant women with placenta previa performed electron microscopy of the myometrium of the lower uterine segment during placenta previa, which formed the main group. The control group included 6 pregnant women within 38 weeks with a normal location of the placenta. In all pregnant women of the main group, myometrial biopsies were taken in the placenta previa of the lower uterine segment. Results and their conclusions. The study found that the most significant electron microscopic changes were found in the myometrium, which is primarily related to the contractile function of smooth myocytes. Obviously, this is due to lack of energy supply, resulting in a decrease in both the number of mitochondria and their functional state. This process is also complicated by other energy sources – trophic inclusions. The condition of blood vessels at presentation of a placenta also changes, both a hypoxic condition of vessels, and surrounding fabrics develops. The detected electron microscopic changes of the placenta give an understanding of the further course of pregnancy and fetal development, because it is the placenta that ensures the interaction of the mother and fetus.


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How to Cite
Lakatosh, P. V., Stechenko, L. O., Lakatosh, V. P., Poladich, I. V., Antonyuk, M. I., & Dola, O. L. (2021). ELECTRON-MICROSCOPIC FEATURES OF THE LOWER UTERINE SEGMENT MYOMETRY IN WOMEN WITH PLACENTAL PRESENTATION. Likarsʹka Sprava, (3-4). https://doi.org/10.31640/JVD.3-4.2021(6)
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