THE STATE OF HOMEOSTASIS IN PATIENTS WITH INFECTIOUS ECZEMA

  • V. І. Khrushch Odessa national medical university
  • H. V. Pavlenko Odessa national medical university
  • V. V. Shukhtin Odessa national medical university
  • І. N. Shukhtina Odessa national medical university
Keywords: infectious eczema, pathogenic, immune system, hemostasis system.

Abstract

The article is devoted to the study of the state of homeostasis systems in patients with infectious eczema and the establishment of the relationship of the hemostatic system and immune status in the patient’s body. Examination of 108 patients with infectious eczema aged 18 to 65 years living in the southern region of Ukraine showed hypercoagulation changes in the hemostatic system and immune imbalance, which depend on the severity of the disease and play an important pathogenetic role in the onset and progression of this pathology. We have established close pathogenetic mechanisms of the relationship between the immune system and the hemostatic system (changes in the vascular-platelet link are associated with changes in humoral immunity – the content of, circulating immune complexes IgE), and coagulation hemostasis disorders – with indicators of cellular immunity (CD3 +, CD4 +, CD8 +, immunoregulatory index). Identified violations of hemostasis and immune status indicate the need to develop a pathogenetically substantiated method of complex individualized therapy for patients with infectious eczema.

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References

Abdrahimova A. A., Nadyrchenko R. M., Mustafina N. R. i dr. Effektivnost' tradicionnoj terapii pri mikrobnoj ekzeme // Med. vestn. Bashkortostana. – 2013. – T. 8, № 4. – Р. 32–35.

Bakulev A. L., Kravchenya S. S., Murashkin N. N. i dr. Mikrobnaya ekzema: novye vozmozhnosti kombinirovannoj topicheskoj terapii // Vestn. dermatologii i venerologii. – 2011. – № 6. – Р. 27–33.

Bolotna L. A. Mіkrobna ekzema: mozhlivostі kombіnovanoї topіchnoї terapії / Ukr. zhurn. dermatologії, venerologії, kosmetologії. – 2015. – Vip. 56, № 1. – Р. 79–84.

Bolotnaya L. A. Novye podhody k naruzhnoj terapii hronicheskoj ekzemy // Tam zhe. – 2012. – Vip. 45, № 2. – Р. 68–75.

Іshchejkіn K. Є., Kajdashev І. P., Stepanenko V. І. Іmunnij status organіzmu dіtej, hvorih na atopіchnij dermatit і dityachu ekzemu // Tam samo. – 2008. – № 4. – Р. 60–62.

Kajdashev І. P., Popova І. B. Rіven' specifіchnogo IgG4 do alergenіv deyakih plіsnyavih gribіv u hvorih na hronіchnu mіkrobnu ekzemu // Tam samo. – 2007. – № 4. – Р. 57–59.

Kalyuzhna L. D., Rodinenko V. M. Osoblivostі patogenezu ekzemi, sprichinenoї varikoznim sindromom u zhіnok perimenopauzal'nogo vіku // Tam samo. – 2005. – № 3. – Р. 142–143.

Kiravan Zaher. Osobennosti sootnoshenij kletok immunnoj sistemy perifericheskoj krovi u bol'nyh mikrobnoj i istinnoj ekzemoj // Dermatovenerologiya. Kosmetologiya. Seksopatologiya. – 2008. – Vyp. 11, № 1–2. – Р. 264–266.

Kovalyova L. N. Pokazateli svertyvayushchej sistemy krovi pri psoriaze i ekzeme // Vestn. dermatologii i venerologii. – 1970. – № 7. – Р. 14–16.

Litins'ka T. O. Rol' ta mіsce dezіntoksikacіjnih metodіv u kompleksnomu lіkuvannі pacієntіv zі shkіrnimi hvorobami // Ukr. zhurn. dermatologії, venerologії, kosmetologії. – 2008. – № 4. – Р. 18–20.

Popova І. B. Stan іmunіtetu u hvorih na mіkrobnu ekzemu z mіkogennoyu alergієyu : Avtoref. dis. … d-ra med. nauk. – Donec'k, 2009. – 18 р.

Smolienko V. N. Etiopatogeneticheskie osobennosti mikrobnoj ekzemy v sochetanii s varikoznoj bolezn'yu // Ukr. zhurn. dermatologії, venerologії, kosmetologії. – 2013. – Vip. 48, № 1. – Р. 77–80.


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Published
2019-06-16
How to Cite
KhrushchV. І., Pavlenko, H. V., Shukhtin, V. V., & Shukhtina І. N. (2019). THE STATE OF HOMEOSTASIS IN PATIENTS WITH INFECTIOUS ECZEMA. Likarsʹka Sprava, (4), 8-15. https://doi.org/10.31640/JVD.4.2019(2)
Section
Immunopathology of human