Treatment of patients with diffuse large B-cell lymphoma from high-risk group

  • K. S. Filonenko National Cancer Institute
  • I. A. Kriachok National Cancer Institute
  • A. V. Martynchyk National Cancer Institute
Keywords: diffuse large B-cell lymphoma, high-risk group, risk factors, therapy, rituximab, survival


Diffuse large B-cell lymphoma (DLBCL) is potentially curative disease. Nevertheless this group of patients is very heterogeneous. There are several scales for the assessment of the disease risk. According to the International Prognostic index 5-year overall survival of patients from high-risk group is 26 % comparing to 73 % in patients from low-risk group. There is no standard approach to the treatment of patients with DLBCL from high-risk group. The literature review of the efficacy of different treatment regimens in patients with DLBCL from high-risk group is presented in the article.


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Filonenko, K. S., Kriachok, I. A., & Martynchyk, A. V. (2017). Treatment of patients with diffuse large B-cell lymphoma from high-risk group. Likars’ka Sprava, (1-2), 9-19.
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