IMMUNE IMBALANCE IN THE PATHOGENESIS OF ABDOMINAL SEPSIS IN THE PATIENTS WITH THE PRIMARY AND SECONDARY LIVER ABSCESSES.FEATURES OF THE DIAGNOSTICS AND OPTIMIZATION OF COMPLEX TREATMENT
Abstract
The purpose ofourworkwas to identify markers of immune imbalance in the patients with abdominal sepsis due toprimary and secondary liver abscesses, to study methods of the correction of the infraction in the organism and a volume of the infusion. There were analyzed the results of treatment of 64 patients with primary and secondary liver abscesses.The results of analysis indicate a pronounced immune imbalance and the formation of secondary immune deficiency at the T-suppressor type. The main stage of the treatment of abdominal sepsis due to primary and secondary abscesses is draining the source of infection with antibacterial, hepatoprotective and detoxification therapy.
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References
2. Mal'ceva L. A., Mosencev N. F., Letuchaya L. A. Abdominal'nyj sepsis: klyuchevye voprosy diagnostiki i intensivnoj terapii // Ukr. zhurn. ekstrem. medicini іm. G. O. Mozhaєva. – 2011. – T. 12, № 4. – S. 5–10.
3. Sepsis: klassifikaciya, kliniko-diagnosticheskaya koncepciya, lechenie / Pod red. B. C. Savel'eva, B. R. Gel'fanda. – 2-e izd., dop. i pererab. – M.: OOO «Med. inform. Agentstvo», 2010. – 352 s.
4. Hernеndez-Palazуn J., Fuentes-Garcнa D., Burguillos-Lуpez S. et al. Analysis of organ failure and mortality in sepsis due to secondaryperitonitis // Med. Intensiva. – 2013. – Vol. 37, N 7. – Р. 461–467.
5. Howell Michael D., Davis Andrew M. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) // JAMA. – 2016. – Vol. 315, N 8. – P. 801–810. Doi:10.1001/jama.2016.0287.
6. Ihnet P., Peteja M., Vevra P. et al. Current standards of care in the management of patients with abdominal sepsis // Rozhl. Chir. – 2015. – Vol. 94, N 6. – Р. 234–237.
7. Jianfang Z., Chuanyum Q., Mingyan Z. et al. Epidemiology and Outcome of Severe Sepsis and Septic Shock in Intensive Care Units in Mainland China // PLОS One. – 2014. – Vol. 16, N 9. – Р. 141–147.
8. Monti G., Landoni G., Taddeo D. Clinical aspects of sepsis: an overview // Methods Mol. Biol. – 2015. – Vol. 37, N 12. – Р. 17–33.
9. Rhodes Andrew, Evans Laura E. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsisand Septic Shock // Critical Care Med. and Intensive Care Med. – 2016. – Vol. 45, N 3. – P. 1–67.
10. Sartelli Massimo, Catena Fausto, Di Saverio Salomone et al. Current concept of abdominal sepsis: WSES position paper // World J. of Emergency Surgery. – 2014. – N 9. – Р. 16–21.
11. Vollmar B. Pathophysiological basis of surgery-linked sepsis // Chirurg. – 2011. – Vol. 82, N 3. – Р. 199–207.
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