Efficacy of Nucleo C. M. P. Forte in Restorative Therapy after Nerve Injury

  • O. S. Barylo Vinnytsia National Pirogov Memorial Medical University, Department of Surgical Dentistry and Maxillo-Facial Surgery
  • S. S. Polishchuk Vinnytsia National Pirogov Memorial Medical University, Department of Surgical Dentistry and Maxillo-Facial Surgery
  • R. L. Furman Vinnytsia National Pirogov Memorial Medical University, Department of Surgical Dentistry and Maxillo-Facial Surgery
  • T. R. Zakalata Vinnytsia National Pirogov Memorial Medical University, Department of Surgical Dentistry and Maxillo-Facial Surgery
Keywords: mandibular fracture, nerve injury, Nucleo C. M. P. Forte, ultrastructure

Abstract

Experimental modelling of nerve injury was carried out by its clamping and subsequent treat- ment with drug product Nucleo C. M. P. Forte. Ultrastructural study of femoral nerve after clamping detected significant dystrophic and destructive changes in axoplasm of axis cylinders of nerve fibers in rats not treated with the drug. Treatment with Nucleo C. M. P. Forte was found to be associated with significantly less pronounced ultrastructural changes as compared to the rat sreceiving no treatment after femoral nerve clamping. Taking into consideration all abovementioned ultrastructural morphological signs, it can be confidently stated that this drug product improves the recovery of nerve fiber, actingas a neuroprotective and restorative agentat tissue and cellular levels.

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Abstract views: 634
PDF Downloads: 308
Published
2017-09-30
How to Cite
Barylo, O. S., Polishchuk, S. S., Furman, R. L., & Zakalata, T. R. (2017). Efficacy of Nucleo C. M. P. Forte in Restorative Therapy after Nerve Injury. Likars’ka Sprava, (5-6), 150-157. https://doi.org/10.31640/LS-2017(5-6)27
Section
Experimental researches